Invention Grant
- Patent Title: Synthesis of boronic ester and acid compounds
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Application No.: US14991363Application Date: 2016-01-08
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Publication No.: US09862745B2Publication Date: 2018-01-09
- Inventor: Vince Ammoscato , John E. Bishop , Fang-Ting Chiu , Achim Geiser , Jean-Marc Gomez , Robert Hett , Christoph Koellner , Vithalanand R. Kulkarni , Young Lo , Stephen Munk , I. Fraser Pickersgill
- Applicant: Millennium Pharmaceuticals, Inc
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Honigman Miller Schwartz and Cohn LLP
- Main IPC: C07F5/02
- IPC: C07F5/02 ; C07K5/06 ; C07F5/04
Abstract:
The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
Public/Granted literature
- US20160362449A1 SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS Public/Granted day:2016-12-15
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