Invention Grant
- Patent Title: High affinity T cell receptor and use thereof
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Application No.: US14224525Application Date: 2014-03-25
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Publication No.: US09862755B2Publication Date: 2018-01-09
- Inventor: Dolores Jean Schendel , Susanne Wilde , Bernhard Frankenberger , Wolfgang Uckert
- Applicant: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN
- Applicant Address: DE Berlin
- Assignee: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN
- Current Assignee: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN
- Current Assignee Address: DE Berlin
- Agency: Clark & Elbing LLP
- Priority: EP08020396 20081124
- Main IPC: C07K14/725
- IPC: C07K14/725 ; A61K35/17 ; A61K38/17 ; C12N15/85
Abstract:
The present invention is directed to a high affinity T cell receptor (TCR) against a tumor-associated antigen, an isolated nucleic acid molecule encoding same, a T cell expressing said TCR, and a pharmaceutical composition for use in the treatment of diseases involving malignant cells expressing said tumor-associated antigen.
Public/Granted literature
- US20140348805A1 HIGH AFFINITY T CELL RECEPTOR AND USE THEREOF Public/Granted day:2014-11-27
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