Invention Grant
- Patent Title: Composition and method for preventing or treating a tauopathy
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Application No.: US14863997Application Date: 2015-09-24
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Publication No.: US09862761B2Publication Date: 2018-01-09
- Inventor: Scott Thomas Brady , Lester I. Binder , Gerardo Andres Morfini , Nicholas M. Kanaan , Nichole E. LaPointe
- Applicant: The Board of Trustees of the University of Illinois , Northwestern University
- Applicant Address: US IL Urbana US IL Evanston
- Assignee: The Board of Trustes of the University of Illinois,Northwestern University
- Current Assignee: The Board of Trustes of the University of Illinois,Northwestern University
- Current Assignee Address: US IL Urbana US IL Evanston
- Agency: Licata & Tyrrell P.C.
- Main IPC: C07K16/18
- IPC: C07K16/18 ; A61K39/395 ; C07K14/47 ; G01N33/50 ; A61K38/00
Abstract:
The present invention is a composition and method for the prevention and treatment of a tauopathy. The composition of the invention includes N-terminal amino acid residues of the tau protein, which have been identified as being involved in toxic activation of a PP1/GSK3 signaling cascade and inhibition of fast axonal transport in human tauopathies.
Public/Granted literature
- US20160031978A1 COMPOSITION AND METHOD FOR PREVENTING OR TREATING A TAUOPATHY Public/Granted day:2016-02-04
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