Invention Grant
- Patent Title: Single domain antibodies against SOD1 and their use in medicine
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Application No.: US14894980Application Date: 2014-05-28
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Publication No.: US09862777B2Publication Date: 2018-01-09
- Inventor: Wim Robberecht , Frederic Rousseau , Joost Schymkowitz
- Applicant: VIB VZW , Life Sciences Research Partners VZW , Katholieke Universiteit Leuven, K.U.Leuven R&D
- Applicant Address: BE Ghent BE Leuven BE Leuven
- Assignee: VIB VZW,LIFE SCIENCES RESEARCH PARTNERS VZW,KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D
- Current Assignee: VIB VZW,LIFE SCIENCES RESEARCH PARTNERS VZW,KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D
- Current Assignee Address: BE Ghent BE Leuven BE Leuven
- Agency: TraskBritt, P.C.
- Priority: EP13169476 20130528
- International Application: PCT/EP2014/061129 WO 20140528
- International Announcement: WO2014/191493 WO 20141204
- Main IPC: C07K16/40
- IPC: C07K16/40 ; A61K39/395 ; A61K39/00
Abstract:
The present application relates to the field of single-domain antibodies (also called nanobodies), more particularly single-domain antibodies against SOD1 protein isoforms. It also relates to the use of these nanobodies in medicine. Accordingly, methods to treat a disease using these nanobodies are provided herein. The single-domain antibodies are particularly envisaged for treatment of ALS.
Public/Granted literature
- US20160115245A1 SINGLE DOMAIN ANTIBODIES AGAINST SOD1 AND THEIR USE IN MEDICINE Public/Granted day:2016-04-28
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