Invention Grant
- Patent Title: Dendritic cell vaccines
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Application No.: US13011798Application Date: 2011-01-21
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Publication No.: US09862927B2Publication Date: 2018-01-09
- Inventor: Jacques F. Banchereau , Monica Montes , Anna Karolina Palucka , Louis M. Sloan , Yves Levy
- Applicant: Jacques F. Banchereau , Monica Montes , Anna Karolina Palucka , Louis M. Sloan , Yves Levy
- Applicant Address: US TX Dallas FR Paris
- Assignee: Baylor Research Institute,Agence Nationale de Recherches Sur le Sida Et Les Hepatitis Virales
- Current Assignee: Baylor Research Institute,Agence Nationale de Recherches Sur le Sida Et Les Hepatitis Virales
- Current Assignee Address: US TX Dallas FR Paris
- Agency: Norton Rose Fulbright US LLP
- Main IPC: A61K39/21
- IPC: A61K39/21 ; C12N5/0784 ; C07K14/005 ; A61K39/12 ; A61K39/00
Abstract:
Compositions and methods for the prophylaxis and treatment of human immunodeficiency virus (HIV) infections are disclosed herein. More specifically the present invention discloses describes an autologous dendritic cell (DC) vaccine product derived by culturing a patient's monocytes with granulocyte macrophage colony stimulating factor (GM-CSF) and interferon alpha 2b (IFN-α), loading the DC with a mixture of five lipopeptides of Gag, Nef and Pol HIV antigens, and, optionally activating the DC with lipopolysaccharide (LPS).
Public/Granted literature
- US20110182937A1 Dendritic Cell Vaccines Public/Granted day:2011-07-28
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