Invention Grant
- Patent Title: CMV glycoproteins and recombinant vectors
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Application No.: US14086602Application Date: 2013-11-21
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Publication No.: US09862972B2Publication Date: 2018-01-09
- Inventor: Louis Picker , Klaus Früh , Scott Hansen
- Applicant: Oregon Health & Science University
- Applicant Address: US OR Portland
- Assignee: Oregon Health & Science University
- Current Assignee: Oregon Health & Science University
- Current Assignee Address: US OR Portland
- Agency: Schwabe, Williamson & Wyatt, P.C.
- Main IPC: C12N15/86
- IPC: C12N15/86 ; C12N7/00 ; A61K39/12 ; A61K39/00
Abstract:
Disclosed herein are recombinant CMV vectors which may comprise a heterologous antigen that can repeatedly infect an organism while inducing a CD8+ T cell response to immunodominant epitopes of the heterologous antigen. The CMV vector may comprise a deleterious mutation in the US11 glycoprotein or a homolog thereof.
Public/Granted literature
- US20140141038A1 CMV GLYCOPROTEINS AND RECOMBINANT VECTORS Public/Granted day:2014-05-22
Information query
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