Invention Grant
- Patent Title: Methods of hydrolyzing a cellulose using halophilic, thermostable and ionic liquids tolerant cellulases
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Application No.: US15164813Application Date: 2016-05-25
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Publication No.: US09862982B2Publication Date: 2018-01-09
- Inventor: Tao Zhang , Supratim Datta , Blake A. Simmons , Edward M. Rubin
- Applicant: The Regents of the University of California , Sandia Corporation
- Applicant Address: US CA Oakland US NM Albuquerque
- Assignee: The Regents of the University of California,Sandia Corporation
- Current Assignee: The Regents of the University of California,Sandia Corporation
- Current Assignee Address: US CA Oakland US NM Albuquerque
- Agency: Lawrence Berkeley National Laboratory
- Agent Robin C. Chiang
- Main IPC: C12P19/14
- IPC: C12P19/14 ; C12P19/02 ; C12N9/42
Abstract:
The present invention provides for an isolated or recombinant polypeptide comprising an amino acid sequence having at least 70% identity with the amino acid sequence of a Halorhabdus utahensis cellulase, such as Hu-CBH1, wherein said amino acid sequence has a halophilic thermostable and/or thermophilic cellobiohydrolase (CBH) activity. In some embodiments, the polypeptide has a CBH activity that is resistant to up to about 20% of ionic liquids. The present invention also provides for compositions comprising and methods using the isolated or recombinant polypeptide.
Public/Granted literature
- US20170029856A1 Useful halophilic, thermostable and ionic liquids tolerant cellulases Public/Granted day:2017-02-02
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