Invention Grant
- Patent Title: Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
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Application No.: US14384581Application Date: 2013-03-13
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Publication No.: US09862995B2Publication Date: 2018-01-09
- Inventor: Abhijit Ajit Patel
- Applicant: Abhijit Ajit Patel
- Agency: Barnes & Thornburg LLP
- International Application: PCT/US2013/031014 WO 20130313
- International Announcement: WO2013/138510 WO 20130919
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Methods and compositions are disclosed for measuring low-abundance DNA variants from a complex mixture of DNA molecules. Embodiments of the methods allow for extremely sensitive detection and can distinguish true variants from sequencer misreads and PCR misincorporations.
Public/Granted literature
- US20150087535A1 MEASUREMENT OF NUCLEIC ACID VARIANTS USING HIGHLY-MULTIPLEXED ERROR-SUPPRESSED DEEP SEQUENCING Public/Granted day:2015-03-26
Information query
