A tamper resistant box includes: a front panel; a side panel attached to the front panel at a first fold line; a back panel attached to the side panel at a second fold line; a side top flap attached to the side panel at a third fold line; and a front top flap attached to the front panel at a fourth fold line. In some examples, the side top flap can define a tapered slot extending towards the third fold line from an edge of the side top flap at a location distal from the third fold line, and a widest portion of the tapered slot can define a tapered slot width. In further examples, the front top flap can define a top slot having a top slot width that is less than the tapered slot width.