Invention Grant
- Patent Title: Anti-Notch3 antibodies
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Application No.: US14653684Application Date: 2013-12-19
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Publication No.: US09879083B2Publication Date: 2018-01-30
- Inventor: Heidi Okamura , Sandra Abbott , Alisa C. Bell , Kelly Kreuter , Ronan O'Hagan , Samantha Perino , Hamid Tissire , William M. Winston, Jr. , Jeno Gyuris
- Applicant: AVEO Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- International Application: PCT/US2013/076615 WO 20131219
- International Announcement: WO2014/100435 WO 20140626
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K16/28 ; A61K39/395 ; C12N15/09 ; C12N15/63 ; C12N5/10 ; C12N5/12 ; C12N5/16 ; C07K14/705 ; C07K14/71 ; A61K39/00
Abstract:
Monoclonal antibodies that bind and inhibit activation of human Notch3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of Notch3.
Public/Granted literature
- US20160185852A1 ANTI-NOTCH3 ANTIBODIES Public/Granted day:2016-06-30
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