Invention Grant
- Patent Title: Method for predicting the responsiveness a patient to a treatment with an anti-CD20 antibody
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Application No.: US15121864Application Date: 2015-02-27
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Publication No.: US09879325B2Publication Date: 2018-01-30
- Inventor: Johanna Chiche , Catherine Thieblemont , Jean-Ehrland Ricci
- Applicant: ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS , UNIVERSITÉ PARIS DIDEROT (PARIS VII) , UNIVERSITÉ DE NICE—SOPHIA ANTIPOLIS , INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE
- Applicant Address: FR Paris FR Paris FR Nice FR Paris
- Assignee: ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS,UNIVERSITÉ PARIS DIDEROT (PARIS VII),UNIVERSITÉ DE NICE—SOPHIA ANTIPOLIS,INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE
- Current Assignee: ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS,UNIVERSITÉ PARIS DIDEROT (PARIS VII),UNIVERSITÉ DE NICE—SOPHIA ANTIPOLIS,INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE
- Current Assignee Address: FR Paris FR Paris FR Nice FR Paris
- Agency: Whitham, Curtis & Cook, P.C.
- Priority: EP14305297 20140303
- International Application: PCT/EP2015/054209 WO 20150227
- International Announcement: WO2015/132163 WO 20150911
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/30 ; G01N33/53 ; C12Q1/68 ; G01N33/50 ; G01N33/574 ; C07K16/28
Abstract:
The present invention relates to a method for predicting the responsiveness of a patient to a treatment with an anti-CD20 antibody, said method comprising measuring the level of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) expression in B cells obtained from said patient.
Public/Granted literature
- US20170073762A1 A METHOD FOR PREDICTING THE RESPONSIVENESS A PATIENT TO A TREATMENT WITH AN ANTI-CD20 ANTIBODY Public/Granted day:2017-03-16
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