Invention Grant
- Patent Title: Pharmaceutical formulations for subcutaneous administration of furosemide
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Application No.: US14781706Application Date: 2014-04-03
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Publication No.: US09884039B2Publication Date: 2018-02-06
- Inventor: Scott A. Michaels , Pieter Muntendam , Glenn R. Larsen
- Applicant: scPharmaceuticals Inc.
- Applicant Address: US MA Burlington
- Assignee: scPharmaceuticals Inc.
- Current Assignee: scPharmaceuticals Inc.
- Current Assignee Address: US MA Burlington
- Agency: Goodwin Procter LLP
- International Application: PCT/US2014/032800 WO 20140403
- International Announcement: WO2014/165660 WO 20141009
- Main IPC: A61K31/341
- IPC: A61K31/341 ; A61K47/18 ; A61K9/00 ; A61K9/08 ; A61K31/635 ; A61K47/02
Abstract:
The present teachings relate to liquid pharmaceutical formulations of furosemide, where the pharmaceutical formulations include a molar excess of tris(hydroxymethyl)aminomethane to furosemide, have a pH in the range of 7 to 8.5, and a concentration of tris(hydroxymethyl)aminomethane greater than or equal to about 50 mM. The present teachings can improve the stability of liquid pharmaceutical formulations including furosemide and the suitability of such pharmaceutical formulations for subcutaneous administration or delivery.
Public/Granted literature
- US20160051507A1 Pharmaceutical Formulations for Subcutaneous Administration of Furosemide Public/Granted day:2016-02-25
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