- Patent Title: Methods for the regulation of matrix metalloproteinase expression
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Application No.: US14898999Application Date: 2014-06-24
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Publication No.: US09884085B2Publication Date: 2018-02-06
- Inventor: D. Travis Wilson , Robert A. Kloner
- Applicant: Stealth BioTherapeutics Corp
- Applicant Address: MC Monaco
- Assignee: STEALTH BIOTHERAPEUTICS CORP
- Current Assignee: STEALTH BIOTHERAPEUTICS CORP
- Current Assignee Address: MC Monaco
- Agency: Foley & Lardner LLP
- International Application: PCT/US2014/043950 WO 20140624
- International Announcement: WO2014/210062 WO 20141231
- Main IPC: A61K38/55
- IPC: A61K38/55 ; A61K38/07 ; A61K45/06 ; A61K31/401
Abstract:
The disclosure provides methods of reducing MMP-9 expression and/or MMP-9 activity in a mammalian subject. The disclosure also provides methods of increasing TIMP-1 expression and/or TIMP-1 activity in a mammalian subject. The methods comprise administering a therapeutically effective amount of an aromatic-cationic peptide to a subject in need thereof.
Public/Granted literature
- US20160151445A1 METHODS FOR THE REGULATION OF MATRIX METALLOPROTEINASE EXPRESSION Public/Granted day:2016-06-02
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