Invention Grant
- Patent Title: Ligand-targeted molecules and methods thereof
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Application No.: US14370524Application Date: 2013-01-03
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Publication No.: US09884123B2Publication Date: 2018-02-06
- Inventor: Shiladitya Sengupta , Sazid Hussain , Dipankar Pramanik , Monideepa Roy , Seikh Samad Hossain
- Applicant: INVICTUS ONCOLOGY PVT. LTD.
- Applicant Address: IN Delhi
- Assignee: INVICTUS ONCOLOGY PVT. LTD.
- Current Assignee: INVICTUS ONCOLOGY PVT. LTD.
- Current Assignee Address: IN Delhi
- Agency: Nixon Peabody LLP
- Agent David S. Resnick
- Priority: IN18/DEL/2012 20120103
- International Application: PCT/US2013/020130 WO 20130103
- International Announcement: WO2013/103707 WO 20130711
- Main IPC: A61K47/48
- IPC: A61K47/48 ; A61K47/68 ; A61K47/00 ; A61K31/282 ; C07F15/00 ; A61K47/50 ; A61K47/60

Abstract:
The present invention relates to ligand-targeted molecules and ligand drug conjugates (LDCs) comprising a ligand connected to a functional group, which is connected to a linker, which in turn is bonded to a drug. The LDCs of the present invention also comprise platinum coordination complex wherein the platinum is connected to the linker through monocarboxylato and O→Pt coordinate bonds. The present invention also relates to methods for preparing these ligand drug conjugates. The present invention further relates to methods for the treatment of tumours using the ligand drug conjugates of the present invention.
Public/Granted literature
- US20150045428A1 LIGAND-TARGETED MOLECULES AND METHODS THEREOF Public/Granted day:2015-02-12
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