The invention relates to a motor spindle comprising at least one spindle drive which can be supplied with energy and/or operating supplies via at least one feed line. This motor spindle has a fixedly installed first coupling element of a multi-coupling, to the ports of which the feed lines for transmitting energy and/or operating supplies are connected. The invention also relates to a machine tool comprising such a motor spindle, wherein the machine tool has a second coupling element of the multi-coupling. On this second coupling element, the respective complementary ports for transmitting energy and/or operating supplies are arranged.