Invention Grant
- Patent Title: Preparation of an intermediate compound of ioforminol
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Application No.: US14430155Application Date: 2013-09-17
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Publication No.: US09884808B2Publication Date: 2018-02-06
- Inventor: Mikkel Jacob Thaning, Jr. , Andreas Olsson , Christian Glogard
- Applicant: GE Healthcare AS
- Applicant Address: NO Oslo
- Assignee: GE Healthcare AS
- Current Assignee: GE Healthcare AS
- Current Assignee Address: NO Oslo
- Agency: Wood IP LLC
- Priority: NO20121102 20120927
- International Application: PCT/US2013/060081 WO 20130917
- International Announcement: WO2014/052091 WO 20140304
- Main IPC: C07C231/14
- IPC: C07C231/14 ; C07C231/02 ; C07C231/24 ; C07C237/46
Abstract:
The present invention relates to a process for the preparation of iodinated X-ray contrast agents and in particular to key intermediates thereof. More particularly, the invention relates to a work-up process for preparation of a compound mixture comprising 1-formylamino-3,5-bis(2,3-bis(formyloxy)propan-1-ylcarbamoyl)-2,4,6-trioodobenzene, a key intermediate in the process for preparing Ioforminol. Further, the invention relates to a process for preparing Ioforminol, a contrast agent useful in X-ray imaging.
Public/Granted literature
- US20150246871A1 PREPARATION OF AN INTERMEDIATE COMPOUND OF IOFORMINOL Public/Granted day:2015-09-03
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