Invention Grant
- Patent Title: Sulphamoylpyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
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Application No.: US14891864Application Date: 2014-05-16
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Publication No.: US09884818B2Publication Date: 2018-02-06
- Inventor: Koen Vandyck , Geerwin Yvonne Paul Haché , Stefaan Julien Last , David Craig Mc Gowan , Geert Rombouts , Wim Gaston Verschueren , Pierre Jean-Marie Bernard Raboisson
- Applicant: Janssen Sciences Ireland UC
- Applicant Address: IE Co Cork
- Assignee: JANSSEN SCIENCES IRELAND UC
- Current Assignee: JANSSEN SCIENCES IRELAND UC
- Current Assignee Address: IE Co Cork
- Priority: EP13168291 20130517; EP13175181 20130704; EP13182281 20130829; EP13191209 20131031; EP13198160 20131218; EP14157900 20140305
- International Application: PCT/EP2014/060102 WO 20140516
- International Announcement: WO2014/184350 WO 20141120
- Main IPC: C07D207/36
- IPC: C07D207/36 ; C07D403/12 ; C07D405/12 ; A61K31/401 ; C07D207/40 ; A61K45/06
Abstract:
Inhibitors of HBV replication of Formula (ID) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, Ra to Rd and R4 to R6 have the meaning as defined herein. The present invention also relates to processes for preparing compounds of Formula (ID), pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
Public/Granted literature
- US20160115125A1 SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B Public/Granted day:2016-04-28
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