Invention Grant
- Patent Title: Tetrahydrocarbazole inhibitors of SIRT1 receptors
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Application No.: US15400144Application Date: 2017-01-06
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Publication No.: US09884819B2Publication Date: 2018-02-06
- Inventor: Chengzhi Zhang , Ralph Laufer
- Applicant: Auspex Pharmaceuticals, Inc.
- Applicant Address: US PA Frazer
- Assignee: Auspex Pharmaceuticals, Inc.
- Current Assignee: Auspex Pharmaceuticals, Inc.
- Current Assignee Address: US PA Frazer
- Agency: Baker & Hostetler LLP
- Main IPC: C07D209/86
- IPC: C07D209/86 ; A61K45/06 ; A61K31/403 ; A61K31/4704
Abstract:
Described are deuterium-substituted tetrahydrocarbazole compounds of Formulae I, II, or III which are inhibitors of sirtuin 1 (SIRT1). Also described are pharmaceutical compositions comprising the deuterium-substituted tetrahydrocarbazole compounds, and methods of use thereof.
Public/Granted literature
- US20170190664A1 Tetrahydrocarbazole Inhibitors Of SIRT1 Receptors Public/Granted day:2017-07-06
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