Invention Grant
- Patent Title: Sulfonamide compounds and uses as TNAP inhibitors
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Application No.: US15241905Application Date: 2016-08-19
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Publication No.: US09884826B2Publication Date: 2018-02-06
- Inventor: Anthony B. Pinkerton , Russell Dahl , Nicholas D. P. Cosford , Jose Luis Millan
- Applicant: Sanford-Burnham Medical Research Institute
- Applicant Address: US CA La Jolla
- Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- Current Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- Current Assignee Address: US CA La Jolla
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C07D213/58
- IPC: C07D213/58 ; C07D401/12 ; A61K31/44 ; C07D213/74 ; A61P19/00 ; C07D213/76 ; C07D215/38 ; A61K31/50 ; C07D401/04 ; C07D405/04 ; C07D405/12 ; C07D409/04 ; C07D409/12 ; C07D417/04 ; C07D213/80 ; C07D213/82 ; C07D231/42 ; C07D333/36 ; C07D237/20 ; C07D239/69 ; C07D241/22 ; C07D261/16 ; C07D263/50 ; C07D271/113 ; C07D277/52 ; C07D285/135 ; C07D213/79 ; C07D213/81 ; C07D215/48
Abstract:
Described herein are compounds that modulate the activity of TNAP. In some embodiments, the compounds described herein inhibit TNAP. In certain embodiments, the compounds described herein are useful in the treatment of conditions associated with hyper-mineralization.
Public/Granted literature
- US20160355479A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS Public/Granted day:2016-12-08
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