Invention Grant
- Patent Title: Salt and crystal forms of PLK-4 inhibitor
-
Application No.: US15029373Application Date: 2014-10-17
-
Publication No.: US09884855B2Publication Date: 2018-02-06
- Inventor: Peter Brent Sampson , Miklos Feher , Heinz W. Pauls
- Applicant: University Health Network
- Applicant Address: CA Toronto
- Assignee: University Health Network
- Current Assignee: University Health Network
- Current Assignee Address: CA Toronto
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- International Application: PCT/CA2014/051001 WO 20141017
- International Announcement: WO2015/054793 WO 20150423
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/14

Abstract:
A fumarate salt and a maleate salt of compound (I) represented by the following structural formula, as well as their corresponding pharmaceutical compositions, are disclosed. Particular single crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are characterized by a variety of properties and physical measurements. Methods of preparing specific crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are also disclosed. The present invention also provides methods of treating a subject with a cancer. Compound
Public/Granted literature
- US20160264559A1 SALT AND CRYSTAL FORMS OF PLK-4 INHIBITOR Public/Granted day:2016-09-15
Information query