Invention Grant
- Patent Title: Solid form of pyrazolopyridine compound
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Application No.: US15027432Application Date: 2014-10-15
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Publication No.: US09884859B2Publication Date: 2018-02-06
- Inventor: Shouzhu Liao , Weijie Fan , Zhongqing Wang
- Applicant: SUNSHINE LAKE PHARMA CO., LTD.
- Applicant Address: CN Dongguan, Guangdong
- Assignee: SUNSHINE LAKE PHARMA CO., LTD.
- Current Assignee: SUNSHINE LAKE PHARMA CO., LTD.
- Current Assignee Address: CN Dongguan, Guangdong
- Agency: Squire Patton Boggs (US) LLP
- Agent Kam W. Law
- Priority: CN201310487493 20131017
- International Application: PCT/CN2014/088680 WO 20141015
- International Announcement: WO2015/055124 WO 20150423
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/506

Abstract:
A novel crystalline form or amorphous of formula (I) and preparation method thereof are disclosed in present invention, wherein the novel crystalline form is substantially pure crystalline form I, form II, form III or form IV. The novel crystalline forms disclosed herein have good solubility, low hydroscopicity and good stability at high temperature (60° C.), high humidity (RH is 90%±5%) and/or under light (4500+/−500 Lux), which benefit for storage, meet the requirements of drug stability and therefore, making formula (I) suitable for formulation preparation and with high bioavailability.
Public/Granted literature
- US20160251349A1 SOLID FORM OF PYRAZOLOPYRIDINE COMPOUND Public/Granted day:2016-09-01
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