Invention Grant
- Patent Title: Ibrutinib solid forms and production process therefor
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Application No.: US15128856Application Date: 2015-03-23
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Publication No.: US09884869B2Publication Date: 2018-02-06
- Inventor: Itai Adin , Sonia Krivonos , Yevgeny Rozenblat , Alex Weisman , Ana Fernadez Casares , Gloria Ten Figas , Revital Ben-Daniel
- Applicant: PERRIGO API LTD.
- Applicant Address: IL Bnei Brak
- Assignee: PERRIGO API LTD.
- Current Assignee: PERRIGO API LTD.
- Current Assignee Address: IL Bnei Brak
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/IL2015/000017 WO 20150323
- International Announcement: WO2015/145415 WO 20151001
- Main IPC: C07D487/00
- IPC: C07D487/00 ; C07D487/04

Abstract:
Provided are ibrutinib polymorphs, e.g., crystalline ibrutinib Forms III, IV, V, VI, VII, VIII and Form IX and processes for producing these crystalline forms, stable amorphous ibrutinib and processes for preparing stable amorphous ibrutinib, pharmaceutical compositions comprising these forms and methods of using these crystalline and amorphous forms.
Public/Granted literature
- US20170226108A1 IBRUTINIB SOLID FORMS AND PRODUCTION PROCESS THEREFOR Public/Granted day:2017-08-10
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