Invention Grant
- Patent Title: Double-stranded polynucleotide
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Application No.: US13001714Application Date: 2009-06-30
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Publication No.: US09885036B2Publication Date: 2018-02-06
- Inventor: Makoto Koizumi , Yasuhide Hirota
- Applicant: Makoto Koizumi , Yasuhide Hirota
- Applicant Address: JP Tokyo
- Assignee: Daiichi Sankyo Company, Limited
- Current Assignee: Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Tokyo
- Agency: Dorsey & Whitney LLP
- Priority: JP2008-172174 20080701; JP2009-122742 20090521
- International Application: PCT/JP2009/061998 WO 20090630
- International Announcement: WO2010/001909 WO 20100107
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K31/713
Abstract:
It is intended to provide a double-stranded polynucleotide that is resistant to RNase and has RNA interference effect, etc. The present invention provides a double-stranded polynucleotide comprising sense and antisense strands comprising polynucleotides comprising a nucleotide unit of DNAs and 2′-O-methyl RNAs alternately combined.
Public/Granted literature
- US20110152353A1 DOUBLE-STRANDED POLYNUCLEOTIDE Public/Granted day:2011-06-23
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