Invention Grant
- Patent Title: Process of preparing functionalized polymers via enzymatic catalysis
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Application No.: US14244018Application Date: 2014-04-03
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Publication No.: US09885070B2Publication Date: 2018-02-06
- Inventor: Judit E Puskas , Mustafa Yasin Sen
- Applicant: THE UNIVERSITY OF AKRON
- Applicant Address: US OH Akron
- Assignee: The University of Akron
- Current Assignee: The University of Akron
- Current Assignee Address: US OH Akron
- Agency: Renner, Kenner, Greive, Bobak, Taylor & Weber
- Main IPC: C08F8/10
- IPC: C08F8/10 ; C12P9/00 ; C08G65/332 ; C08G65/333 ; C08G77/38 ; C08L71/02 ; C12P7/62

Abstract:
The invention relates to functionalized, telechelic polymers synthesized by enzymatic catalysis and methods, and the functionalization of polymers via Michael addition with a lipase catalyst, and the crosslinking of mono- or difunctional (telechelic) polymers made by enzymatic catalysis, such as by using multifunctional coupling agents and enzyme catalysts. Quantitative transesterification of vinyl methacrylate with poly(ethylene glycol), poly(isobutylene) and poly(dimethylsiloxane) was achieved using Candida antarctica lipase B. In addition, methacrylate-functionalized poly(ethylene glycol) monomethyl ether has been successfully coupled to aminoethoxy poly(ethylene glycol) monomethyl ether via Michael addition using Candida antarctica lipase B. Amine-functionalized poly(ethylene glycol)s have also been used for the preparation of poly(ethylene glycol)-based dendrimers and gels through Michael addition of the polymer onto triacryloyl hexahydro-triazine using the same enzyme. 1H and 13C NMR spectroscopy verified the structure of the functionalized polymers.
Public/Granted literature
- US20140273111A1 PROCESS OF PREPARING FUNCTIONALIZED POLYMERS VIA ENZYMATIC CATALYSIS Public/Granted day:2014-09-18
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