A method for fluidly sealing two conduits having mating surfaces is described. The method includes positioning a gasket between the surfaces, securing the two conduits together with the gasket interposed between the mating surfaces wherein the gasket includes an outer seal with a first thickness and an inner seal with a thickness greater than that of the outer seal. The step of positioning and/or the step of securing includes compressing the thickness of the inner seal. Methods of making the gaskets are also disclosed.