- Patent Title: Determination of a midregional proadrenomedullin partial peptide in biological fluids for diagnostic purposes, and immunoassays for carrying out such a determination
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Application No.: US10551298Application Date: 2004-01-29
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Publication No.: US09885709B2Publication Date: 2018-02-06
- Inventor: Andreas Bergmann , Joachim Struck
- Applicant: Andreas Bergmann , Joachim Struck
- Applicant Address: GR Henningsdorf
- Assignee: B.R.A.H.M.S. GMBH
- Current Assignee: B.R.A.H.M.S. GMBH
- Current Assignee Address: GR Henningsdorf
- Agency: Millen White Zelano and Branigan, PC
- Agent John Sopp; Csaba Henter
- Priority: DE10316583 20030410
- International Application: PCT/EP2004/000806 WO 20040129
- International Announcement: WO2004/090546 WO 20041021
- Main IPC: G01N33/543
- IPC: G01N33/543 ; G01N33/574 ; G01N33/68 ; G01N33/74
Abstract:
Method for the determination of adrenomedullin immunoreactivity in biological fluids for diagnostic purposes, in particular in sepsis, cardiac and cancer diagnosis, in which the midregional partial peptide (mid-proAM; SEQ ID NO:3) of proadrenomedullin, which comprises the amino acids (45-92) of the complete preproadrenomedullin (pre-proAM; SEQ ID NO:1), is measured in particular by means of an immunoassay which operates with at least one labelled antibody which specifically recognizes a sequence of mid-proAM.
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