A method of enhancing a refresh PCI translation (RPCIT) operation to refresh a translation lookaside buffer (TLB) includes determining, by a computer processor, a request to perform at least one RPCIT instruction for purging at least one translation from the TLB. The method further includes purging, by the computer processor, the at least one translation from the TLB in response to executing the at least one RPCIT instruction. The computer processor selectively performs a synchronization operation prior to completing the at least one RPCIT instruction.