Invention Grant
- Patent Title: Diaminopyrimidine derivatives and processes for the preparation thereof
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Application No.: US14001489Application Date: 2012-02-24
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Publication No.: US09890138B2Publication Date: 2018-02-13
- Inventor: Hyun-Joo Lee , Dong-Hoon Kim , Tae-Kyun Kim , Young-Ae Yoon , Jae-Young Sim , Myung-Hun Cha , Eun-Jung Jung , Kyoung-Kyu Ahn , Tai-Au Lee
- Applicant: Hyun-Joo Lee , Dong-Hoon Kim , Tae-Kyun Kim , Young-Ae Yoon , Jae-Young Sim , Myung-Hun Cha , Eun-Jung Jung , Kyoung-Kyu Ahn , Tai-Au Lee
- Applicant Address: KR Seoul
- Assignee: YUHAN CORPORATION
- Current Assignee: YUHAN CORPORATION
- Current Assignee Address: KR Seoul
- Agency: Vorys, Sater, Seymour and Pease LLP
- Agent Mih Suhn Koh
- Priority: KR10-2011-0016981 20110225
- International Application: PCT/KR2012/001427 WO 20120224
- International Announcement: WO2012/115480 WO 20120830
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D401/04 ; C07D413/04 ; C07D413/14 ; C07D417/04

Abstract:
The present invention provides a diaminopyrimidine derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same, and a use thereof. The diaminopyrimidine derivative or its pharmaceutically acceptable salt functions as a 5-HT4 receptor agonist, and therefore can be usefully applied for preventing or treating dysfunction in gastrointestinal motility, one of the gastrointestinal diseases, such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, or diabetic gastric atony.
Public/Granted literature
- US20150274700A2 DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Public/Granted day:2015-10-01
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