Invention Grant
- Patent Title: Compounds and method for treating autoimmune diseases
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Application No.: US14750794Application Date: 2015-06-25
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Publication No.: US09890144B2Publication Date: 2018-02-13
- Inventor: Esteban Masuda , Rajinder Singh , Vanessa Taylor , Donald G. Payan
- Applicant: Rigel Pharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Klarquist Sparkman, LLP
- Agent Travis Young
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/675 ; C07D413/12 ; C07F9/653 ; A61K45/06

Abstract:
Compounds and embodiments of a method for treating and/or preventing autoimmune diseases are disclosed. The method includes administering to a subject having an autoimmune disease, such as an inflammatory bowel disease, a therapeutically effective amount of a compound according to formula I wherein X and Y independently are O or NR1; each R1 is independently H or C1-C6 alkyl; ring A is aryl; each R2 independently is H, alkyl, alkoxy, amide, cyano, halo, haloalkyl, hydroxyalkyl, heteroalkyl, heterocyclyl, sulfonyl, sulfonamide, or two R2 groups, taken together with the atom or atoms to which they are attached, combine to form a 4-10 membered ring system; p is 0, 1, 2, 3, or 4; R3 and R4 independently are H or C1-C6 alkyl; and R5 is halo, cyano, or C1-C6 alkyl.
Public/Granted literature
- US20150313899A1 COMPOUNDS AND METHOD FOR TREATING AUTOIMMUNE DISEASES Public/Granted day:2015-11-05
Information query
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