Invention Grant
- Patent Title: Staphylococcus aureus SpA5 mutant, composition comprising mutant and preparation method and use thereof
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Application No.: US15103173Application Date: 2013-12-09
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Publication No.: US09890199B2Publication Date: 2018-02-13
- Inventor: Quanming Zou , Hao Zeng , Shaowen Fan , Lu Lu , Qiang Feng , Jinyong Zhang , Haiming Jing , Yandong Dong , Yi Wu , Changzhi Cai
- Applicant: OLYMVAX BIOPHARMACEUTICALS INC. , THIRD MILITARY MEDICAL UNIVERSITY, PLA
- Applicant Address: CN Chengdu CN Chongqing
- Assignee: Olymvax Biopharmaceuticals Inc.,Third Military Medical University, PLA
- Current Assignee: Olymvax Biopharmaceuticals Inc.,Third Military Medical University, PLA
- Current Assignee Address: CN Chengdu CN Chongqing
- Agency: Calfee, Halter & Griswold LLP
- International Application: PCT/CN2013/088880 WO 20131209
- International Announcement: WO2015/085463 WO 20150618
- Main IPC: C07K14/31
- IPC: C07K14/31 ; A61K39/085 ; G01N33/569 ; A61K39/40 ; C07K16/12 ; C12N15/70 ; A61K39/00
Abstract:
Provided is staphylococcus protein A expressed by a mutational Staphylococcus aureus and its coding sequence, as well as a vector, host bacteria, composition or kit which contains the coding sequence of the mutational protein. Also provided is the use of the mutational protein and the composition thereof in the preparation of vaccines, therapeutic antibodies, diagnostic kits and the like, and for the prevention, treatment and detection of infections by Staphylococcus aureus. Also provided are methods for producing, fermenting and purifying the mutational protein.
Public/Granted literature
- US20160304566A1 STAPHYLOCOCCUS AUREUS SPA5 MUTANT, COMPOSITION COMPRISING MUTANT AND PREPARATION METHOD AND USE THEREOF Public/Granted day:2016-10-20
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