Invention Grant
- Patent Title: Antagonist antibodies directed against calcitonin gene-related peptide
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Application No.: US15588461Application Date: 2017-05-05
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Publication No.: US09890211B2Publication Date: 2018-02-13
- Inventor: Joerg Zeller , Kristian T. Poulsen , Yasmina Noubia Abdiche , Jaume Pons , Sierra Jones Collier , Arnon Rosenthal
- Applicant: Teva Pharmaceuticals International GmbH
- Applicant Address: CH Jona
- Assignee: Teva Pharmaceuticals International GmbH
- Current Assignee: Teva Pharmaceuticals International GmbH
- Current Assignee Address: CH Jona
- Agency: Fish & Richardson P.C.
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K16/26 ; A61K31/4045 ; A61K39/395 ; A61K39/00

Abstract:
The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
Public/Granted literature
- US20170240623A1 Antagonist Antibodies Directed Against Calcitonin Gene- Related Peptide Public/Granted day:2017-08-24
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