Invention Grant
- Patent Title: Cellulose ethers esterified with dicarboxylic acid
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Application No.: US14777838Application Date: 2014-05-07
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Publication No.: US09890221B2Publication Date: 2018-02-13
- Inventor: Ligeng Yin , Marc A. Hillmyer , Steven J. Guillaudeu , Robert L. Schmitt
- Applicant: Dow Global Technologies LLC , The Regents of the University of Minnesota
- Applicant Address: US MI Midland US MN Minneapolis
- Assignee: Dow Global Technologies LLC,University of Minnesota
- Current Assignee: Dow Global Technologies LLC,University of Minnesota
- Current Assignee Address: US MI Midland US MN Minneapolis
- International Application: PCT/US2014/037070 WO 20140507
- International Announcement: WO2014/186185 WO 20141120
- Main IPC: C08B13/00
- IPC: C08B13/00 ; A61K9/14 ; A61K31/095 ; A61K31/4166 ; A61K47/38

Abstract:
Esterified cellulose ethers comprising groups of formula —C(O)—CHR′—CHR″—COOA, wherein, R′ and R″ are hydrogen or (—S)m(—R1)n-R2, wherein R1 is a hydrocarbon group having 1 to 4 carbon atoms, R2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR′—CHR″ one of R′ and R″ is hydrogen and the other one is (—S)m(—R1)n-R2, are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels.
Public/Granted literature
- US20160289344A1 CELLULOSE ETHERS ESTERIFIED WITH DICARBOXYLIC ACID Public/Granted day:2016-10-06
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