Invention Grant
- Patent Title: Antisense nucleic acids
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Application No.: US15339069Application Date: 2016-10-31
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Publication No.: US09890381B2Publication Date: 2018-02-13
- Inventor: Naoki Watanabe , Haruna Seo , Shin'ichi Takeda , Tetsuya Nagata
- Applicant: NIPPON SHINYAKU CO., LTD. , NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
- Applicant Address: JP Kyoto-shi, Kyoto JP Kodaira-shi, Tokyo
- Assignee: NIPPON SHINYAKU CO., LTD.,NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
- Current Assignee: NIPPON SHINYAKU CO., LTD.,NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY
- Current Assignee Address: JP Kyoto-shi, Kyoto JP Kodaira-shi, Tokyo
- Agency: Drinker Biddle & Reath LLP
- Priority: JP2011-288040 20111228; JP2012-043092 20120229
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/7115 ; A61K31/712 ; A61K31/7125 ; A61K48/00 ; C12N15/11
Abstract:
The present invention provides a pharmaceutical agent which causes skipping of the 55th, 45th, 50th or 44th exon in the human dystrophin gene with a high efficiency. The present invention provides an oligomer which efficiently enables to cause skipping of the 55th, 45th, 50th or 44th exon in the human dystrophin gene.
Public/Granted literature
- US20170067052A1 ANTISENSE NUCLEIC ACIDS Public/Granted day:2017-03-09
Information query
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