Invention Grant
- Patent Title: Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
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Application No.: US15080101Application Date: 2016-03-24
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Publication No.: US09890395B2Publication Date: 2018-02-13
- Inventor: Trevor Collingwood , Gregory J. Cost
- Applicant: Sangamo BioSciences, Inc.
- Applicant Address: US CA Richmond
- Assignee: Sangamo Therapeutics, Inc.
- Current Assignee: Sangamo Therapeutics, Inc.
- Current Assignee Address: US CA Richmond
- Agency: Pasternak Patent Law
- Agent Susan Abrahamson
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12N15/09 ; C12N15/90 ; C07K14/47 ; C12N9/10 ; C12N15/85 ; C12N15/87 ; C12P21/00
Abstract:
Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
Public/Granted literature
- US20160194665A1 METHODS AND COMPOSITIONS FOR INACTIVATING ALPHA 1,6 FUCOSYLTRANSFERASE (FUT8) GENE EXPRESSION Public/Granted day:2016-07-07
Information query
