A piston slide valve including a valve housing, a piston slide mounted movably in the valve housing, which is reciprocally movable in the valve housing and configured to manipulate a fluid flow, and a valve drive. The valve drive includes a rotatable drive shaft, which is mechanically connected to the piston slide via a mechanical coupling. The mechanical coupling includes an actuating element which is eccentrically mounted on the rotatable drive shaft and which engages with a coupling piece that is attached to a radial outside of the piston slide, wherein either the actuating element has a spherical outer surface, which engages into said cylindrical opening of said coupling piece, or the coupling piece has an outer surface, which engages into a cylindrical opening of the actuating element.