- Patent Title: Systems and methods for single-molecule detection using nanotubes
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Application No.: US15646880Application Date: 2017-07-11
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Publication No.: US09891182B2Publication Date: 2018-02-13
- Inventor: Sebastian Sorgenfrei , Kenneth Shepard , Chien-Yang Chiu , Colin Nuckolls , Steven Warren
- Applicant: The Trustees of Columbia University in the City of New York
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Baker Botts L.L.P.
- Main IPC: G01N27/327
- IPC: G01N27/327 ; G01N27/04 ; C12Q1/68
Abstract:
A method for single-molecule detection is provided and uses a carbon nanotube having a probe entity attached thereto to define a first state of the carbon nanotube. The carbon nanotube is introduced to a target entity to define a second state of the carbon nanotube. The electrical conductance of the carbon nanotube in the first and second states is compared to detect the presence of a biomolecular entity. A system for single-molecule detection including a carbon nanotube is also provided.
Public/Granted literature
- US20170350837A1 SYSTEMS AND METHODS FOR SINGLE-MOLECULE DETECTION USING NANOTUBES Public/Granted day:2017-12-07
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