Invention Grant
- Patent Title: Microarray device for screening or locating HSP90 inhibitors or inhibitors of further disease-relevant target structures
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Application No.: US14128298Application Date: 2012-04-20
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Publication No.: US09891230B2Publication Date: 2018-02-13
- Inventor: Dieter Melzner , Thomas Scheper , Thomas Schueler , Frank Stahl , Denise Van Rossum , Johanna-Gabriela Walter , Carsten Zeilinger
- Applicant: Dieter Melzner , Thomas Scheper , Thomas Schueler , Frank Stahl , Denise Van Rossum , Johanna-Gabriela Walter , Carsten Zeilinger
- Applicant Address: DE
- Assignee: SARTORIUS STEDIM BIOTECH GMBH
- Current Assignee: SARTORIUS STEDIM BIOTECH GMBH
- Current Assignee Address: DE
- Agency: McDonald Hopkins LLC
- Priority: DE102011106984 20110708
- International Application: PCT/EP2012/001725 WO 20120420
- International Announcement: WO2013/007324 WO 20130117
- Main IPC: G01N33/543
- IPC: G01N33/543 ; G01N33/68

Abstract:
The present invention relates to a microarray device for the screening or the finding of protein inhibitors, to a method for the production thereof, and to a corresponding method for screening or finding protein inhibitors. The microarray device according to the invention comprises a solid supporting element having a support material, at least one protein immobilized thereon for which inhibitors are to be screened or found, and at least one known inhibitor of the at least one protein, the inhibitor being bound to the at least one protein and comprising a detectable label.
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