The present invention discloses a method and access network device for interference coordination, said method comprises: getting time-frequency resource of cell, and dividing said time-frequency resource into multiple resource subsets; grouping users to be scheduled in the cell into multiple user groups according to AOA, the amount of said user groups is equal to the amount of said resource subsets, different user groups have different resource subset selection priority orders; allocating time-frequency resource of the resource subsets to users, which are in neighboring cells and have the same direction, according to said resource subset selection priority orders of the user groups. The present invention could reduce inter-cell co-frequency interference and improve channel quality.