A combination toothbrush and toothpaste dispenser device includes a caddy that accepts tube of toothpaste and guides an integral toothpaste squeezer along a predetermined track. The squeezer is generally wedge-shaped and may be moved parallel and/or inwardly to the axis of the caddy. A modular and detachable toothbrush head mates with the caddy and includes a shaft with a central bore for delivering toothpaste to the toothbrush bristles. A refresh cup is further supplied to store and protect the combination device while not in use.