Invention Grant
- Patent Title: Stable MIA/CD-RAP formulation
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Application No.: US15336155Application Date: 2016-10-27
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Publication No.: US09907829B2Publication Date: 2018-03-06
- Inventor: Klaus Hellerbrand , Rainer Sigl
- Applicant: Scil Technology GmbH
- Applicant Address: DE Martinsried
- Assignee: SCIL TECHNOLOGY GMBH
- Current Assignee: SCIL TECHNOLOGY GMBH
- Current Assignee Address: DE Martinsried
- Agency: Kagan Binder, PLLC
- Priority: EP10161160 20100427
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/16 ; A61K38/17 ; A61K9/00 ; A61K47/22 ; C07K14/47 ; C07K14/78 ; A61K47/24

Abstract:
The present invention relates to stable aqueous formulations comprising at least 5 mg/mL CD-RAP and a charged amino acid, said amino acid preferably having a net charge at a pH between about 6 and 8. The ingredients of the formulation preferably provide stability over repeated freeze-thaw cycles. In a preferred aspect, the formulation is for use in therapy, preferably for use in the treatment of inflammatory disorders, preferably osteoarthritis. Furthermore, a kit comprising the formulation of the invention is provided.
Public/Granted literature
- US20170042971A1 STABLE MIA/CD-RAP FORMULATION Public/Granted day:2017-02-16
Information query
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