Invention Grant
- Patent Title: Combination of a PD-1 antagonist and a listeria-based vaccine for treating prostate cancer
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Application No.: US14802607Application Date: 2015-07-17
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Publication No.: US09907849B2Publication Date: 2018-03-06
- Inventor: Robert Petit , David J. Mauro , Rodolfo F. Perini
- Applicant: Advaxis, Inc. , Merck Sharp and Dohme Corp.
- Applicant Address: US NJ Princeton US NJ Rahway
- Assignee: Advaxis, Inc.,Merck Sharp & Dohme Corp.
- Current Assignee: Advaxis, Inc.,Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Princeton US NJ Rahway
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A61K39/395 ; A61K39/00
Abstract:
The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a Listeria based strain that expresses prostate-tissue specific antigen (PSA), and the use of the combination therapies for the treatment of prostate cancer.
Public/Granted literature
- US20160022814A1 COMBINATION OF A PD-1 ANTAGONIST AND A LISTERIA-BASED VACCINE FOR TREATING PROSTATE CANCER Public/Granted day:2016-01-28
Information query
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