Invention Grant
- Patent Title: Compositions and methods related to protein A (SpA) antibodies as an enhancer of immune response
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Application No.: US14968023Application Date: 2015-12-14
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Publication No.: US09907850B2Publication Date: 2018-03-06
- Inventor: Olaf Schneewind , Alice Cheng , Dominique M. Missiakas , Hwan Keun Kim
- Applicant: The University of Chicago
- Applicant Address: US IL Chicago
- Assignee: The University of Chicago
- Current Assignee: The University of Chicago
- Current Assignee Address: US IL Chicago
- Agency: Norton Rose Fulbright US LLP
- Main IPC: A61K39/40
- IPC: A61K39/40 ; C07K16/12 ; A61K39/085 ; A61K39/39 ; A61K39/00
Abstract:
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant or an antibody directed thereto.
Public/Granted literature
- US20160175441A1 COMPOSITIONS AND METHODS RELATED TO PROTEIN A (SPA) ANTIBODIES AS AN ENHANCER OF IMMUNE RESPONSE Public/Granted day:2016-06-23
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