- Patent Title: Room temperature ferromagnetic gadolinium silicide nanoparticles
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Application No.: US15332940Application Date: 2016-10-24
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Publication No.: US09907865B2Publication Date: 2018-03-06
- Inventor: Magundappa Ravi L. Hadimani , Shalabh Gupta , Shane Harstad , Vitalij Pecharsky , David C. Jiles
- Applicant: Magundappa Ravi L. Hadimani , Shalabh Gupta , Shane Harstad , Vitalij Pecharsky , David C. Jiles
- Applicant Address: US IA Ames
- Assignee: Iowa State University Research Foundation, Inc.
- Current Assignee: Iowa State University Research Foundation, Inc.
- Current Assignee Address: US IA Ames
- Agency: Reinhart Boerner Van Deuren P.C.
- Main IPC: A61K49/06
- IPC: A61K49/06 ; C01B33/06 ; A61K49/18
Abstract:
A particle usable as T1 and T2 contrast agents is provided. The particle is a gadolinium silicide (Gd5Si4) particle that is ferromagnetic at temperatures up to 290 K and is less than 2 μm in diameter. An MRI contrast agent that includes a plurality of gadolinium silicide (Gd5Si4) particles that are less than 1 μm in diameter is also provided. A method for creating gadolinium silicide (Gd5Si4) particles is also provided. The method includes the steps of providing a Gd5Si4 bulk alloy; grinding the Gd5Si4 bulk alloy into a powder; and milling the Gd5Si4 bulk alloy powder for a time of approximately 20 minutes or less.
Public/Granted literature
- US20170119909A1 ROOM TEMPERATURE FERROMAGNETIC GADOLINIUM SILICIDE NANOPARTICLES Public/Granted day:2017-05-04
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