A fuel cap cover is provided which protects its user from the spread of pathogens and inhibits contact with noxious chemicals such as liquid fuel residues in a fuel station environment. The fuel cap cover fits conveniently over the fuel cap in the fuel supply inlet enclosure when not in use. The fuel cap cover is flexible and has pockets which conveniently fit over the user's thumb and fingers. It is dimensioned to readily grasp and manipulate the fuel pump handle, operational controls, and other surfaces in a fuel station environment, and then slip easily off and back onto the fuel cap to be stored until its next use.