An antimicrobial barrier seatbelt covering apparatus for preventing a cross contamination between hosts contacting with a seatbelt includes stripes of antimicrobial material creating a barrier against pathogens accumulated on a seatbelt, a container for storage of the antimicrobial material that can be attached on one end of the seatbelt, and a holding device to fix the material on the other end of the seatbelt. The antimicrobial seatbelt covering may be used in applications including seatbelts in cars seats, airplanes, boats where the seatbelt covering controls the level of cross contamination by preventing unwanted microbes that contact the seatbelt and thereby, prevents the spread of disease and infections.