Invention Grant
- Patent Title: Compounds useful for treating aids
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Application No.: US14256334Application Date: 2014-04-18
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Publication No.: US09908869B2Publication Date: 2018-03-06
- Inventor: Jamal Tazi , Florence Mahuteau , Romain Najman , Didier Scherrer , Noelie Campos , Aude Garcel
- Applicant: SOCIETE SPLICOS , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , INSTITUT CURIE , UNIVERSITE MONTPELLIER 2
- Applicant Address: FR Paris FR Paris FR Paris FR Montpellier
- Assignee: ABIVAX,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,INSTITUT CURIE,UNIVERSITE DE MONTPELLIER
- Current Assignee: ABIVAX,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,INSTITUT CURIE,UNIVERSITE DE MONTPELLIER
- Current Assignee Address: FR Paris FR Paris FR Paris FR Montpellier
- Agency: Oliff PLC
- Priority: EP09162630 20090612; EP09305540 20090612
- Main IPC: C07D215/38
- IPC: C07D215/38 ; A61K31/4709 ; C07D403/12 ; A61K31/4985 ; C07D213/74 ; C07D241/44 ; C07D401/12 ; C07D215/42 ; C07D215/46

Abstract:
A compound having the following formula or a pharmaceutically acceptable salt thereof: where: R″ is a hydrogen atom or a (C1-C4)alkyl group; n′ is 1 or 2; n is 1, 2, or 3; R independently represents a hydrogen atom, a halogen atom, or a group selected from a (C1-C3)alkyl group, a —CN group, a hydroxyl group, a —NR1R2 group, a —COOR1 group, a (C1-C3)fluoroalkyl group, a —NO2 group, a (C1-C3)fluoroalkoxy, and a (C1-C4)alkoxy group; R′ is a hydrogen atom, a halogen atom, or a group selected from a (C1-C3)alkyl group, a —COOR1 group, a —NO2 group, a —NR1R2 group, a (C1-C4)alkoxy group, and a CN group; R1 and R2 are a hydrogen atom or a (C1-C3)alkyl group; with the proviso that when R and R′ are not simultaneously a hydrogen atom: when n is 1, R is not a methyl group in an ortho or para position with respect to N, when R′ is a hydrogen atom, R is not a bromine atom or a chlorine atom, and when R is a hydrogen atom, R′ is not a methyl or ethyl group, a —COOH group, a —COOC2H5 group, or a bromine atom that is in an ortho position of the bond linked to NR″.
Public/Granted literature
- US20140288120A1 COMPOUNDS USEFUL FOR TREATING AIDS Public/Granted day:2014-09-25
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