- Patent Title: Process for the preparation of apixaban and intermediates thereof
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Application No.: US15282373Application Date: 2016-09-30
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Publication No.: US09908881B2Publication Date: 2018-03-06
- Inventor: Dhananjay G Sathe , Arijit Das , Yashwant Surve , Ramdas N. Ahire
- Applicant: Unichem Laboratories Limited
- Applicant Address: IN Maharastra
- Assignee: Unichem Laboratories Limited
- Current Assignee: Unichem Laboratories Limited
- Current Assignee Address: IN Maharastra
- Agency: Cesari and McKenna, LLP
- Priority: IN2833/MUM/2014 20140905; IN2690/MUM/2015 20150716
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D211/86
Abstract:
The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides process for preparation of Apixaban using a different sequence of synthetic steps and does not involve use of Ullmann reaction.
Public/Granted literature
- US20170015663A1 PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF Public/Granted day:2017-01-19
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