Invention Grant
- Patent Title: Bromodomain inhibitors
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Application No.: US15130503Application Date: 2016-04-15
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Publication No.: US09908885B2Publication Date: 2018-03-06
- Inventor: Michael John Bennett , Juan Manuel Betancort , Amogh Boloor , Stephen W. Kaldor , Jeffrey Alan Stafford , James Marvin Veal
- Applicant: Celgene Quanticel Research, Inc.
- Applicant Address: US CA San Diego
- Assignee: CELGENE QUANTICEL RESEARCH, INC.
- Current Assignee: CELGENE QUANTICEL RESEARCH, INC.
- Current Assignee Address: US CA San Diego
- Agency: Wiley Rein LLP
- Main IPC: C07D417/04
- IPC: C07D417/04 ; C07D473/34 ; C07D405/04 ; C07D401/04 ; C07D413/04 ; C07D471/04 ; C07D491/04 ; C07D401/14 ; C07D413/14 ; C07D471/06 ; C07D498/04
Abstract:
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.
Public/Granted literature
- US20170050968A1 BROMODOMAIN INHIBITOR Public/Granted day:2017-02-23
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