Invention Grant
![Processes for preparing pyrazolyl-substituted pyrrolo[2,3-d]pyrimidines](/docs/US/2018-03-06/US09908888B2/abs.jpg.600x600.jpg)
- Patent Title: Processes for preparing pyrazolyl-substituted pyrrolo[2,3-d]pyrimidines
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Application No.: US15016918Application Date: 2016-02-05
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Publication No.: US09908888B2Publication Date: 2018-03-06
- Inventor: Jiacheng Zhou , Pingli Liu , Qiyan Lin , Brian W. Metcalf , David Meloni , Yongchun Pan , Michael Xia , Mei Li , Tai-Yuen Yue , James D. Rodgers , Haisheng Wang
- Applicant: Incyte Holdings Corporation , Incyte Corporation
- Applicant Address: US DE Wilmington US DE Wilmington
- Assignee: Incyte Corporation,Incyte Holdings Corporation
- Current Assignee: Incyte Corporation,Incyte Holdings Corporation
- Current Assignee Address: US DE Wilmington US DE Wilmington
- Agency: Lathrop Gage LLP
- Agent Brian C. Trinque
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D231/10 ; C07F7/18 ; C07F7/10 ; C07F5/02 ; C07F7/08
![Processes for preparing pyrazolyl-substituted pyrrolo[2,3-d]pyrimidines](/abs-image/US/2018/03/06/US09908888B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
Public/Granted literature
- US20160257687A1 PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS Public/Granted day:2016-09-08
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