Invention Grant
- Patent Title: P2X7 receptor antagonists and agonists
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Application No.: US14403754Application Date: 2013-05-31
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Publication No.: US09908935B2Publication Date: 2018-03-06
- Inventor: Welbeck Owusu Danquah , Friedrich Nolte , Catelijne Stortelers , Toon Laeremans
- Applicant: Ablynx N.V.
- Applicant Address: BE Ghent-Zwijnaarde DE Hamburg
- Assignee: Ablynx N.V.,University Medical Center Hamburg-Eppendorf
- Current Assignee: Ablynx N.V.,University Medical Center Hamburg-Eppendorf
- Current Assignee Address: BE Ghent-Zwijnaarde DE Hamburg
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/EP2013/061257 WO 20130531
- International Announcement: WO2013/178783 WO 20131205
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C12N5/10 ; C07K14/705 ; A61K39/00
Abstract:
The present invention relates to biological materials against P2X7 and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the biological materials of the present invention inhibit the biological activity of the P2X7 receptor, such as activation by ATP.
Public/Granted literature
- US20150133637A1 P2X7 RECEPTOR ANTAGONISTS AND AGONISTS Public/Granted day:2015-05-14
Information query
